Niosome: A future of targeted drug delivery systems

Ketousetuo Kuotsu, KaziMasud Karim, AsimSattwa Mandal, Nikhil Biswas, Arijit Guha, Sugata Chatterjee, Mamata Behera

Journal of Advanced Pharmaceutical Technology amp Research · 2010 · 589 citations · 20 references

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TL;DR

Recent advances in biotechnology and genetic engineering have transformed infectious disease treatment and immunization, prompting a focus on effective delivery of biologics and leading to the development of niosomes—biodegradable, non‑ionic surfactant vesicles that are nontoxic, stable, inexpensive, and a promising alternative to liposomes. This review examines the expanding interest in niosomes across scientific fields, particularly their medical applications. It also summarizes preparation techniques, niosome types, characterization methods, and their diverse applications.

Abstract

Over the past several years, treatment of infectious diseases and immunisation has undergone a revolutionary shift. With the advancement of biotechnology and genetic engineering, not only a large number of disease-specific biological have been developed, but also emphasis has been made to effectively deliver these biologicals. Niosomes are vesicles composed of non-ionic surfactants, which are biodegradable, relatively nontoxic, more stable and inexpensive, an alternative to liposomes. This article reviews the current deepening and widening of interest of niosomes in many scientific disciplines and, particularly its application in medicine. This article also presents an overview of the techniques of preparation of niosome, types of niosomes, characterisation and their applications.

References

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