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Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors

Maria Letícia de Castro Barbosa, Lı́dia Moreira Lima, Roberta Tesch, Carlos Maurício R. Sant’Anna, Frank Totzke, Michael H.G. Kubbutat, Christoph Schächtele, Stefan Laufer, Eliezer J. Barreiro

European Journal of Medicinal Chemistry · 2013 · 141 citations · 35 references

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35

Development and validation of a genetic algorithm for flexible docking 1 1Edited by F. E. Cohen

Gareth Jones, Peter Willett, Robert C. Glen et al. · Journal of Molecular Biology · 1997 · 6.7K citations

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Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes

Matthew Eldridge, Christopher W. Murray, T.R. Auton et al. · Journal of Computer-Aided Molecular Design · 1997 · 1.7K citations

, , +12

Molecular recognition of receptor sites using a genetic algorithm with a description of desolvation

Gareth Jones, Peter Willett, Robert C. Glen · Journal of Molecular Biology · 1995 · 1.5K citations

, , +15

Empirical Scoring Functions for Advanced Protein−Ligand Docking with PLANTS

Oliver Korb, Thomas Stützle, Thomas E. Exner · Journal of Chemical Information and Modeling · 2009 · 1.3K citations

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Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity

Cai‐Hong Yun, Titus J. Boggon, Yiqun Li et al. · Cancer Cell · 2007 · 1.2K citations · Full text

, , +15