Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors

Maria Letícia de Castro Barbosa, Lı́dia Moreira Lima, Roberta Tesch, +6

European Journal of Medicinal Chemistry

Molecular PharmacologyMedicinal ChemistryVegfr-2 Dual InhibitorsMedicinePharmacotherapy +5

Antihypertensive profile of 2-thienyl-3,4-methylenedioxybenzoylhydrazone is mediated by activation of the A2A adenosine receptor

Carla Moreira Leal, Sharlene Lopes Pereira, Arthur Eugen Kümmerle, +7

European Journal of Medicinal Chemistry

HypertensionAntihypertensive ProfileBiochemistryMedicineAntihypertensive Therapy +5

Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib

Raquel Carvalho Montenegro, Alison Howarth, Alessandro Ceroni, +13

Oncotarget

Beneficial effects of a novel agonist of the adenosine <scp>A_2A</scp> receptor on monocrotaline‐induced pulmonary hypertension in rats

A Alencar, Sharlene Lopes Pereira, Tadeu L. Montagnoli, +12

British Journal of Pharmacology

Structure-Based Design of Selective Salt-Inducible Kinase Inhibitors

Roberta Tesch, Marcel Rak, Monika Raab, +10

Journal of Medicinal Chemistry

N-acylhydrazone derivative ameliorates monocrotaline-induced pulmonary hypertension through the modulation of adenosine AA2R activity

A Alencar, Sharlene Lopes Pereira, Flavia E. da Silva, +12

International Journal of Cardiology

InflammationMolecular PharmacologyHypertensionPulmonary Arterial HypertensionMolecular Physiology +8

Pyridinylimidazoles as dual glycogen synthase kinase 3β/p38α mitogen-activated protein kinase inhibitors

Fabian Heider, Francesco Ansideri, Roberta Tesch, +8

European Journal of Medicinal Chemistry

Molecular PharmacologyBiochemistryMedicineNatural SciencesMechanism Of Action +7

Identification and Further Development of Potent TBK1 Inhibitors

André Richters, Debjit Basu, Julian Engel, +5

ACS Chemical Biology

Drug TargetTool CompoundsPharmacotherapyPharmaceutical ChemistryTumor Biology +14

Fast Iterative Synthetic Approach toward Identification of Novel Highly Selective p38 MAP Kinase Inhibitors

Sandra Röhm, Benedict‐Tilman Berger, Martin Schröder, +10

Journal of Medicinal Chemistry

A Highly Selective Chemical Probe for Activin Receptor-like Kinases ALK4 and ALK5

Thomas Hanke, Jong Fu Wong, Benedict‐Tilman Berger, +7

ACS Chemical Biology

Molecular BiologySubstrate Smad2Chemical BiologySignaling PathwayReceptor Tyrosine Kinase +16