Concepedia

Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy

Kenneth J. Valenzano, Laykea Tafesse, Gary Lee, James Harrison, Jamie Boulet, Susan L. Gottshall, Lilly Mark, Michelle Pearson, Wendy Miller, Shen Shan,

Neuropharmacology · 2005 · 285 citations · 37 references

DOI

Concepts

References

37

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

William A. Devane, Aviva Breuer, Roger G. Pertwee et al. · Science · 1992 · 5.6K citations

, , +15

Molecular characterization of a peripheral receptor for cannabinoids

Sean Munro, Kerrie L. Thomas, Muna Abu-Shaar · Nature · 1993 · 5.1K citations

, , +14

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

Lisa A. Matsuda, Stephen J. Lolait, Michael Brownstein et al. · Nature · 1990 · 5K citations

, , +11

A METHOD FOR DETERMINING LOSS OF PAIN SENSATION

F. E. D'Amour, Donn L. Smith · Journal of Pharmacology and Experimental Therapeutics · 1941 · 3.2K citations

, , +14