MBD2 and MeCP2 regulate distinct transitions in the stage-specific differentiation of olfactory receptor neurons

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Histone Modifications, Chromatin, Dna Methyltransferases Dnmt3a +13

Genome-wide atlas of gene expression in the adult mouse brain

Ed S. Lein, Michael Hawrylycz, Nancy Ao et al. · Nature · 2006 · 5.8K citations

Functional Genomics, Neurogenomics, Cellular Neuroscience +11

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

Ruthie E. Amir, Ignatia B. Van den Veyver, Mimi Wan et al. · Nature Genetics · 1999 · 5K citations

Chromatin, Genome Instability, Transcriptional Regulation +11

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

En Li, Timothy H. Bestor, Rudolf Jaenisch · Cell · 1992 · 3.9K citations

Developmental Biology, Embryonic Lethality, Epigenetic Change +8

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

Xinsheng Nan, Huck‐Hui Ng, Colin A. Johnson et al. · Nature · 1998 · 3.4K citations

Histone Modifications, Chromatin, Transcriptional Regulation +13