Increased activity of 5-lipoxygenase in polymorphonuclear leukocytes from asthmatic patients

Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes

A. W. Ford‐Hutchinson, M.A. Bray, Mira Doig et al. · Nature · 1980 · 2.1K citations

Inflammation, Cytokine, Granulocyte +10

Enhanced Synthesis of Leukotriene B4 by Colonic Mucosa in Inflammatory Bowel Disease

Pinchas Sharon, William F. Stenson · Gastroenterology · 1984 · 749 citations

Inflammation, Chronic Inflammatory Diseases, Anti-inflammatory +8

Lipoxygenation of arachidonic acid as a source of polymorphonuclear leukocyte chemotactic factors in synovial fluid and tissue in rheumatoid arthritis and spondyloarthritis.

Lloyd B. Klickstein, Christine Shapleigh, Edward J. Goetzl · Journal of Clinical Investigation · 1980 · 346 citations · Full text

Lipid Peroxidation, Immunology, Psoriatic Arthritis +19

Arachidonate 5-lipoxygenase of guinea pig peritoneal polymorphonuclear leukocytes. Activation by adenosine 5'-triphosphate.

Kazuhide Ochi, T Yoshimoto, S Yamamoto et al. · Journal of Biological Chemistry · 1983 · 215 citations · Full text

Inhibitory effect of esculetin on 5-lipoxygenase and leukotriene biosynthesis

Tomohiro Neichi, Yasuko Koshihara, Sei‐itsu Murota · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · 1983 · 196 citations

Biosynthesis, Oxysterol, Biochemistry +6