Enhanced Synthesis of Leukotriene B4 by Colonic Mucosa in Inflammatory Bowel Disease

Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes

A. W. Ford‐Hutchinson, M.A. Bray, Mira Doig et al. · Nature · 1980 · 2.1K citations

Life Sciences, Cell Biology, Pharmacology +12

Prostaglandin Endoperoxides. Novel Transformations of Arachidonic Acid in Human Platelets

Mats Hámberg, Bengt Samuelsson · Proceedings of the National Academy of Sciences · 1974 · 1.4K citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response.

Sven‐Erik Dahlén, J Björk, Per Hedqvist et al. · Proceedings of the National Academy of Sciences · 1981 · 1K citations · Full text

Veterinary Medicine, Pharmacology, Inflammation +15

Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation

R.J. Flower, Geoffrey J. Blackwell · Nature · 1979 · 929 citations

Life Sciences, Biochemistry, Pharmacology +16

Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. Formation of a novel dihydroxyeicosatetraenoic acid.

P Borgeat, Bengt Samuelsson · Journal of Biological Chemistry · 1979 · 653 citations · Full text

Life Sciences, Biochemistry, Cellular Metabolism +14