Concepedia

Adenosine triphosphate acts as a paracrine signaling molecule to reduce the motility of T cells

Chiuhui Mary Wang, Cristina Ploia, Fabio Anselmi, Adélaïda Sarukhan, Antonella Viola

The EMBO Journal · 2014 · 64 citations · 58 references

DOIFull text

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Concepts

References

58

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

Silvia Deaglio, Karen M. Dwyer, Wenda Gao et al. · The Journal of Experimental Medicine · 2007 · 2.4K citations · Full text

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A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

Stefan Feske, Yousang Gwack, Murali Prakriya et al. · Nature · 2006 · 2.3K citations

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STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

Shenyuan L. Zhang, Ying Yu, Jack Roos et al. · Nature · 2005 · 1.4K citations · Full text

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Orai1 is an essential pore subunit of the CRAC channel

Murali Prakriya, Stefan Feske, Yousang Gwack et al. · Nature · 2006 · 1.3K citations

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Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression

Giovanna Borsellino, Markus Kleinewietfeld, Diletta Di Mitri et al. · Blood · 2007 · 1.3K citations · Full text

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