Shenyuan L. Zhang

STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

Shenyuan L. Zhang, Ying Yu, Jack Roos et al. · Nature · 2005 · 1.4K citations · Full text

Signal Transduction, Molecular Physiology, Ca2+ Sensor +7

Genome-wide RNAi screen of Ca ²⁺ influx identifies genes that regulate Ca ²⁺ release-activated Ca ²⁺ channel activity

Shenyuan L. Zhang, Andriy V. Yeromin, Xiang H.-F. Zhang et al. · Proceedings of the National Academy of Sciences · 2006 · 849 citations · Full text

Genetics, Molecular Biology, Cytoskeleton +24

Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai

Andriy V. Yeromin, Shenyuan L. Zhang, Weihua Jiang et al. · Nature · 2006 · 796 citations · Full text

Biochemistry, Natural Sciences, Molecular Biology +7

The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers

Aubin Penna, Angelo Demuro, Andriy V. Yeromin et al. · Nature · 2008 · 373 citations · Full text

Stim-induced Dimerization, Molecular Biology, Ion Channels +6

Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation

Maria Lioudyno, J. Ashot Kozak, Aubin Penna et al. · Proceedings of the National Academy of Sciences · 2008 · 260 citations · Full text