MHC allele-specific binding of a malaria peptide makes it become promiscuous on fitting a glycine residue into pocket 6

Structure of the human class I histocompatibility antigen, HLA-A2

Pamela J. Björkman, Mark A. Saper, Boudjéma Samraoui et al. · Nature · 1987 · 3.5K citations

Hla, Histocompatibility, Human Class +7

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

Steven A. Rosenberg, James Chih‐Hsin Yang, Douglas J. Schwartzentruber et al. · Nature Medicine · 1998 · 1.8K citations

Vaccination, Therapeutic Evaluation, Melanoma +10

General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.

Richard A. Houghten · Proceedings of the National Academy of Sciences · 1985 · 1.6K citations · Full text

Peptide Engineering, Immunology, Glycobiology +20

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

Lawrence J. Stern, Jerry H. Brown, Theodore S. Jardetzky et al. · Nature · 1994 · 1.6K citations

Virus Structure, Crystal Structure, Hla Immunogenetics +10

Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices

Tiziana Sturniolo, Elisa Bono, Jiayi Ding et al. · Nature Biotechnology · 1999 · 748 citations

Hla, Histocompatibility, Engineering +17