Dynalign: an algorithm for finding the secondary structure common to two RNA sequences

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text

Life Sciences, Bioinformatics, Sequence Analysis +14

A general method applicable to the search for similarities in the amino acid sequence of two proteins

Saul B. Needleman, Christian D. Wunsch · Journal of Molecular Biology · 1970 · 11.5K citations

Life Sciences, Biochemistry, Bioinformatics +13

Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure

David H. Mathews, Jeffrey Sabina, Michael Zuker et al. · Journal of Molecular Biology · 1999 · 3.9K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +15

Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information

Michael Zuker, Patrick Stiegler · Nucleic Acids Research · 1981 · 3.6K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

The Complete Atomic Structure of the Large Ribosomal Subunit at 2.4 Å Resolution

Nenad Ban, Poul Nissen, J.L. Hansen et al. · Science · 2000 · 3.3K citations

Life Sciences, Biochemistry, Molecular Biology +17