Essential function for the GTPase TC21 in homeostatic antigen receptor signaling

T cell receptor antagonist peptides induce positive selection

Kristin A. Hogquist, Stephen C. Jameson, William R. Heath et al. · Cell · 1994 · 2.8K citations

T-regulatory Cell, Immunology, Positive Selection +7

In Vivo Ablation of Surface Immunoglobulin on Mature B Cells by Inducible Gene Targeting Results in Rapid Cell Death

Kong‐Peng Lam, Ralf Kühn, Klaus Rajewsky · Cell · 1997 · 1.1K citations · Full text

Vivo Ablation, Mature B Cells, Apoptosis +8

An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway

Barbara J. Schiemann, Jennifer L. Gommerman, Kalpit A. Vora et al. · Science · 2001 · 1.1K citations

Lymphocyte Development, Humoral Response, Immunology +22

IL-7 is critical for homeostatic proliferation and survival of naïve T cells

Joyce T. Tan, Eric Dudl, Eric M. Leroy et al. · Proceedings of the National Academy of Sciences · 2001 · 943 citations · Full text

Adaptive Immune System, T-regulatory Cell, Naïve T Cells +17

Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice

Klaus Okkenhaug, Antonio Bilancio, Géraldine Farjot et al. · Science · 2002 · 929 citations

Immunology, Cell Death, Immunologic Mechanism +17