Concepedia

Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles

Sandrine Alais, Sabrina Simoes, Dominique Baas, Sylvain Lehmann, Graça Raposo, Jean Luc Darlix, Pascal Leblanc

Biology of the Cell · 2008 · 138 citations · 37 references

DOI

Abstract

The dissemination of prions in N2a cell culture is mediated through the exosomal pathway.

References

37

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Hadi Valadi, Karin M. Ekström, Apostolos Bossios et al. · Nature Cell Biology · 2007 · 12.6K citations

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Identification and proteomic profiling of exosomes in human urine

Trairak Pisitkun, Rong‐Fong Shen, Mark A. Knepper · Proceedings of the National Academy of Sciences · 2004 · 2.1K citations · Full text

Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery

Janina Ratajczak, Katarzyna Miękus, Magda Kucia et al. · Leukemia · 2006 · 1.6K citations

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Exosomes with Immune Modulatory Features Are Present in Human Breast Milk

Charlotte Admyre, Sara Johansson, Khaleda Rahman Qazi et al. · The Journal of Immunology · 2007 · 1.2K citations · Full text

Cells release prions in association with exosomes

Benoît Février, Didier Vilette, Fabienne Archer et al. · Proceedings of the National Academy of Sciences · 2004 · 976 citations · Full text

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