Surfing the p53 network

Bert Vogelstein, David P. Lane, Arnold J. Levine

Nature

EngineeringNetwork ScienceP53 NetworkNetwork AnalysisInformation Forensics +3

Regulation of chromatin structure by site-specific histone H3 methyltransferases

Stephen Rea, Frank Eisenhaber, Dónal O’Carroll, +8

Nature

Histone ModificationsChromatinTranscriptional RegulationChromatin StructureChromatin Remodeling +10

Negative Control of p53 by Sir2α Promotes Cell Survival under Stress

Jianyuan Luo, Anatoly Nikolaev, Shin‐ichiro Imai, +5

Cell

Cell RegulationCell SignalingApoptosisCell DeathCellular Senescence +7

A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

Gunnar Schotta, Monika Lachner, Kavitha Sarma, +5

Genes & Development

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

Homayoun Vaziri, Samuel Benchimol

Current Biology

Lifespan ExtensionGenome InstabilityNatural SciencesTelomerase ActivityMolecular Biology +6

Regulation of p53 activity through lysine methylation

Sergei Chuikov, Julia K. Kurash, J. Wilson, +9

Nature

ChromatinLysine MethylationMedicineNatural SciencesEpigenetic Change +5

Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation

Kenichi Nishioka, Sergei Chuikov, Kavitha Sarma, +4

Genes & Development

Histone ModificationsEpigenetic ChangeGeneticsDna MethylationMolecular Biology +20

Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1

Joanna Wysocka, Michael P. Myers, Carol D. Laherty, +2

Genes & Development

Histone ModificationsEpigenetic ChangeMolecular BiologyEpigeneticsTranscriptional Regulation +14

Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex

Mark A. Brown, Robert J. Sims, Paul Gottlieb, +1

Molecular Cancer

TP53 mutation spectra and load: a tool for generating hypotheses on the etiology of cancer.

Magali Olivier, S. Perwez Hussain, Claude Caron de Fromentel, +2

PubMed

EngineeringCancer PathologyPathologyP53 ProteinCancer Biology +18