Caffeine tolerance and choice in humans

Tolerance to the humoral and hemodynamic effects of caffeine in man.

David Robertson, Dawn Wade, Robert J. Workman et al. · Journal of Clinical Investigation · 1981 · 506 citations · Full text

Medicine, Nutritional Sciences, Pharmacology +13

Improved gas chromatographic method for the determination of nicotine and cotinine in biologic fluids

Peyton Jacob, Margaret D. Wilson, Neal L. Benowitz · Journal of Chromatography B Biomedical Sciences and Applications · 1981 · 457 citations

Pharmacy, Pharmacology, Toxicology +9

Psychotropic effects of caffeine in man. IV. Quantitative and qualitative differences associated with habituation to coffee

Avram Goldstein, Sophia Kaizer, Owen Whitby · Clinical Pharmacology & Therapeutics · 1969 · 203 citations

Medicine, Pharmacology, Psychology +10

Low-dose caffeine physical dependence in humans.

R R Griffiths, Suzette M. Evans, Stephen J. Heishman et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 185 citations

Medicine, Pharmacology, Psychology +15

Effects of caffeine on alertness

Ardith Zwyghuizen‐Doorenbos, Timothy Roehrs, Lauren Lipschutz et al. · Psychopharmacology · 1990 · 173 citations

Social Sciences, Behavioral Sciences, Psychology +6