Concepedia

Design and synthesis of substituted quinolines as novel and selective melanin concentrating hormone antagonists as anti-obesity agents

Namal C. Warshakoon, Justin Sheville, Ritu Tiku Bhatt, Wei Ji, José Méndez-Andino, Kenneth M. Meyers, Nick Kim, John A. Wos, Chrissy Mitchell, Jennifer L. Paris,

Bioorganic & Medicinal Chemistry Letters · 2006 · 61 citations · 8 references

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References

8

Prevalence and Trends in Obesity Among US Adults, 1999-2000

Katherine M. Flegal · JAMA · 2002 · 6.2K citations

A role for melanin-concentrating hormone in the central regulation of feeding behaviour

Daqing Qu, David S. Ludwig, Steen Gammeltoft et al. · Nature · 1996 · 1.3K citations

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Mice lacking melanin-concentrating hormone are hypophagic and lean

Masako Shimada, Nicholas A. Tritos, Bradford B. Lowell et al. · Nature · 1998 · 1.2K citations

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Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance

David S. Ludwig, Nicholas A. Tritos, Jason Mastaitis et al. · Journal of Clinical Investigation · 2001 · 620 citations · Full text

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The Synthesis of Certain Substituted Quinolines and 5,6-Benzoquinolines

R. Gordon Gould, Walter A. Jacobs · Journal of the American Chemical Society · 1939 · 297 citations

, , +8