Preparation of 1-(2,3-dideoxy-.beta.-D-glycero-pent-2-enofuranosyl)thymine (d4T) and 2',3'-dideoxyadenosine (ddA): general methods for the synthesis of 2',3'-olefinic and 2',3'-dideoxy nucleoside analogs active against HIV

Muzammil M. Mansuri, John E. Starrett, John A. Wos, +4

The Journal of Organic Chemistry

2',3'-Dideoxy Nucleoside AnalogsBioorganic ChemistryAltmetric Attention ScoreOrganic ChemistryAntiviral Drug +15

Design and synthesis of substituted quinolines as novel and selective melanin concentrating hormone antagonists as anti-obesity agents

Namal C. Warshakoon, Justin Sheville, Ritu Tiku Bhatt, +10

Bioorganic & Medicinal Chemistry Letters

Selective MelaninBiochemistryMedicineSynthetic ChemistryPharmacology +4

Effects of β3-Adrenergic Receptor Activation on Rat Urinary Bladder Hyperactivity Induced by Ovariectomy

F. Aura Kullmann, Brian J. Limberg, Debra E. Artim, +6

Journal of Pharmacology and Experimental Therapeutics

Targeting protein tyrosine phosphatase to enhance insulin action for the potential treatment of diabetes.

K. Bhavani, John A. Wos, Kevin G. Peters

PubMed

Metabolic SyndromeProtein Tyrosine PhosphataseInsulin SignalingSignal TransductionInsulin Action +13

The Synthesis and Human FP Receptor Binding Affinity of 13,14-Dihydro Prostaglandin F1.ALPHA. Sulfonamides. Potential Treatments for Osteoporosis.

Yili Wang, David L. Soper, Michelle J. Dirr, +3

Chemical and Pharmaceutical Bulletin

SclerostinPharmacotherapyPharmaceutical ChemistryOsteoporosisMolecular Pharmacology +15

Claisen rearrangements of enol phosphates

Raymond L. Funk, John B. Stallman, John A. Wos

Journal of the American Chemical Society

Molecular SciencesEngineeringChemical AnalysisClaisen RearrangementsDonut Icon +11

Titanium-mediated cyclizations of .beta.-keto esters with acetals: a convenient route to 2-carbalkoxycycloalkenones

Raymond L. Funk, John F. Fitzgerald, Thomas A. Olmstead, +2

Journal of the American Chemical Society

Medicinal ChemistryEngineeringHeterocyclicBiochemistryConvenient Route +12

Design and synthesis of potent and selective 1,3,4-trisubstituted-2-oxopiperazine based melanocortin-4 receptor agonists

Xinrong Tian, Rajesh Mishra, Adrian G. Switzer, +8

Bioorganic & Medicinal Chemistry Letters

Melanocortin-4 Receptor AgonistsMedicinal ChemistryBiochemistryFunctional SelectivityMedicine +4

Discovery of novel conformationally restricted diazocan peptidomimetics as inhibitors of interleukin-1β synthesis

Kofi A. Oppong, Christopher D. Ellis, Michael C. Laufersweiler, +12

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryDrug TargetBiochemistryNatural SciencesMedicine +8

Synthesis and evaluation of novel 8,6-fused bicyclic peptidomimetic compounds as interleukin-1β converting enzyme inhibitors

Steven V. O’Neil, Yili Wang, Michael C. Laufersweiler, +12

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBiochemistryMedicineNatural SciencesEnzyme Inhibitors +4