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Structural characterization of N-linked oligosaccharides on monoclonal antibody cetuximab by the combination of orthogonal matrix-assisted laser desorption/ionization hybrid quadrupole–quadrupole time-of-flight tandem mass spectrometry and sequential enzymatic digestion

Structural CharacterizationBiochemistryNatural SciencesBioanalysisMass SpectrometryBiological Mass SpectrometryGlycobiologyAntibody EngineeringAnalytical UltracentrifugationN-linked OligosaccharidesMedicineMonoclonal Antibody CetuximabBiomolecular EngineeringGlycosylation