Concepedia

Structural characterization of N-linked oligosaccharides on monoclonal antibody cetuximab by the combination of orthogonal matrix-assisted laser desorption/ionization hybrid quadrupole–quadrupole time-of-flight tandem mass spectrometry and sequential enzymatic digestion

Jun Qian, Tun Liu, Li Yang, Ann Daus, Richard M. Crowley, Qinwei Zhou

Analytical Biochemistry · 2007 · 281 citations · 25 references

DOI

Concepts

References

25

Phase II Trial of Cetuximab in Patients With Refractory Colorectal Cancer That Expresses the Epidermal Growth Factor Receptor

Leonard B. Saltz, Neal J. Meropol, Patrick J. Loehrer et al. · Journal of Clinical Oncology · 2004 · 1.7K citations · Full text

Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution.

J. Deisenhofer · PubMed · 1981 · 1.4K citations

, , +11

Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-.ANG. resolution

J. Deisenhofer · Biochemistry · 1981 · 1.3K citations

, , +20

Glycosylation changes of IgG associated with rheumatooid arthritis can activate complement via the mannose-binding protein

Rajneesh Malhotra, Mark R. Wormald, Pauline M. Rudd et al. · Nature Medicine · 1995 · 766 citations

, , +13

Studies of aglycosylated chimeric mouse-human IgG. Role of carbohydrate in the structure and effector functions mediated by the human IgG constant region.

Mi‐Hua Tao, Sherie L. Morrison · The Journal of Immunology · 1989 · 528 citations

, , +20