Concepedia

Synthesis and biological evaluation of benzyl styrylsulfonyl derivatives as potent anticancer mitotic inhibitors

Osama Chahrour, Ashraf N. Abdalla, Frankie Lam, Carol Midgley, Shudong Wang

Bioorganic & Medicinal Chemistry Letters · 2011 · 18 citations · 12 references

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12

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

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ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent

Kiranmai Gumireddy, M. V. Ramana Reddy, Stephen C. Cosenza et al. · Cancer Cell · 2005 · 368 citations · Full text

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2-Anilino-4-(thiazol-5-yl)pyrimidine CDK Inhibitors:  Synthesis, SAR Analysis, X-ray Crystallography, and Biological Activity

Shudong Wang, Christopher Meades, Gavin Wood et al. · Journal of Medicinal Chemistry · 2004 · 153 citations · Full text

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Phase I Study of ON 01910.Na, a Novel Modulator of the Polo-Like Kinase 1 Pathway, in Adult Patients With Solid Tumors

Antonio Jimeno, Jing Li, Wells A. Messersmith et al. · Journal of Clinical Oncology · 2008 · 129 citations · Full text

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Discovery and Characterization of 2-Anilino-4- (Thiazol-5-yl)Pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents

Shudong Wang, Gary Griffiths, Carol Midgley et al. · Chemistry & Biology · 2010 · 101 citations · Full text

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