Gary Griffiths

2-Anilino-4-(thiazol-5-yl)pyrimidine CDK Inhibitors:  Synthesis, SAR Analysis, X-ray Crystallography, and Biological Activity

Shudong Wang, Christopher Meades, Gavin Wood et al. · Journal of Medicinal Chemistry · 2004 · 151 citations · Full text

X-ray Crystallography, Molecular Docking, Medicinal Chemistry +15

Discovery and Characterization of 2-Anilino-4- (Thiazol-5-yl)Pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents

Shudong Wang, Gary Griffiths, Carol Midgley et al. · Chemistry & Biology · 2010 · 101 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +7

Discovery of<i>N</i>-Phenyl-4-(thiazol-5-yl)pyrimidin-2-amine Aurora Kinase Inhibitors

Shudong Wang, Carol Midgley, Frédéric Scaërou et al. · Journal of Medicinal Chemistry · 2010 · 100 citations · Full text

Insights into Cyclin Groove Recognition

George Kontopidis, Martin J. I. Andrews, Campbell McInnes et al. · Structure · 2003 · 63 citations · Full text

Natural Sciences, Signal Recognition, Molecular Biology +8

Synthesis and biological activity of 2-anilino-4-(1H-pyrrol-3-yl) pyrimidine CDK inhibitors

Shudong Wang, Gavin Wood, Christopher Meades et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 60 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Pyrimidine Cdk Inhibitors +3