The mechanism of activation of the alternative pathway of complement by cell-bound C4b

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

Pamela J. Fraker, John C. Speck · Biochemical and Biophysical Research Communications · 1978 · 4.6K citations

Life Sciences, Biochemistry, Cell Biology +8

Formation of the initial C3 convertase of the alternative complement pathway. Acquisition of C3b-like activities by spontaneous hydrolysis of the putative thioester in native C3.

Michael K. Pangburn, Robert D. Schreiber, Hans J. Müller‐Eberhard · The Journal of Experimental Medicine · 1981 · 443 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Complement C3 convertase: Cell surface restriction of β1H control and generation of restriction on neuraminidase-treated cells

Michael K. Pangburn, Hans J. Müller‐Eberhard · Proceedings of the National Academy of Sciences · 1978 · 346 citations · Full text

Life Sciences, Biochemistry, Immunology +14

Common evolutionary origin of alpha 2-macroglobulin and complement components C3 and C4.

Lars Sottrup‐Jensen, T M Stepanik, Torsten Nygaard Kristensen et al. · Proceedings of the National Academy of Sciences · 1985 · 189 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Nucleophilic modification of human complement protein C3: correlation of conformational changes with acquisition of C3b-like functional properties

David E. Isenman, D. I. C. Kells, Neil R. Cooper et al. · Biochemistry · 1981 · 188 citations

Life Sciences, Biochemistry, Immunology +13