Concepedia

Author

David E. Isenman

University of Toronto

Also Known As

D E Isenman, D ISENMAN, D Isenman, D. E. Isenman, D. Isenman, D.E. ISENMAN, D.E. Isenman, David E Isenman, David E. Isenman, David Isenman

102

Publications

4.5K

Citations

39

H-Index

92

Concepts

All Affiliations

University of TorontoUniversity of BathScripps Health
DE

About

David E. Isenman is an author at University of Toronto specializing in medicine, immunology, and molecular biology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

25

36

1.8K

2

Natural Sciences

17

21

857

3

Health Sciences

2

2

105

4

Engineering

1

1

19

5

Social Sciences

1

1

67

David E. Isenman

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68

Publications

4.1K

Citations

38

H-Index

YearCitations

The molecular basis for the difference in immune hemolysis activity of the Chido and Rodgers isotypes of human complement component C4.

David E. Isenman, John R. Young

The Journal of Immunology

1984

240

Dual interaction of factor H with C3d and glycosaminoglycans in host–nonhost discrimination by complement

Tommi Kajander, Markus J. Lehtinen, Satu Hyvärinen,

Proceedings of the National Academy of Sciences

2011

221

X-ray Crystal Structure of C3d: A C3 Fragment and Ligand for Complement Receptor 2

Bhushan Nagar, Russell G. Jones, Russell J. Diefenbach,

Science

1998

202

Nucleophilic modification of human complement protein C3: correlation of conformational changes with acquisition of C3b-like functional properties

David E. Isenman, D. I. C. Kells, Neil R. Cooper,

Biochemistry

1981

188

The structure and function of immunoglobulin domains. II. The importance of interchain disulfide bonds and the possible role of molecular flexibility in the interaction between immunoglobulin G and complement.

David E. Isenman, Keith J. Dorrington, R. H. Painter

PubMed

1975

155

Interaction of Human Complement with Sbi, a Staphylococcal Immunoglobulin-binding Protein

Julia D. Burman, Elisa Leung, Karen Atkins,

Journal of Biological Chemistry

2008

145

Identification of the Fc gamma receptor class I binding site in human IgG through the use of recombinant IgG1/IgG2 hybrid and point-mutated antibodies.

M S Chappel, David E. Isenman, Margaret Everett,

Proceedings of the National Academy of Sciences

1991

128

Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria

Matthew T. Sorbara, Elisabeth G. Foerster, Jessica Tsalikis,

Cell Host & Microbe

2018

122

The Structure and Function of Immunoglobulin Domains

David E. Isenman, Keith J. Dorrington, R. H. Painter

The Journal of Immunology

1975

108

Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.

Michael C. Carroll, D. M. Fathallah, Luigi Bergamaschini,

Proceedings of the National Academy of Sciences

1990

106

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