Concepedia
Biochemical Pharmacology · 1997 · 100 citations · 40 references
Medicinal ChemistryApoptosis InductionOncogenic AgentMedicineApoptosisCell DeathDna IntegrityMgi 114PharmacotherapyAnti-cancer AgentPharmacologyRadiation OncologyCancer ResearchDrug Discovery
40
Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis
A H Wyllie, Russell E. Morris, Alex Smith et al. · The Journal of Pathology · 1984 · 1.6K citations
Apoptosis, Condensed Chromatin Morphology, Molecular Biology +19
Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.
F Oberhammer, James W. Wilson, Caroline Dive et al. · The EMBO Journal · 1993 · 1.1K citations · Full text
Genome Instability, Apoptosis, Kb Fragments +7
Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays.
Wojciech Gorczyca, J Gong, Zbigniew Darżynkiewicz · PubMed · 1993 · 994 citations
Dna Damage, Apoptosis, Dna Analysis +17
Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin
Patricia M. Takahara, Amy C. Rosenzweig, Christin Frederick et al. · Nature · 1995 · 763 citations
Crystal Structure, Medicinal Chemistry, Double-stranded Dna +8
Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C.
W. David Jarvis, Amy Turner, Lawrence F. Povirk et al. · PubMed · 1994 · 355 citations
Hematological Malignancy, Oncology, Protein Kinase C +15