Shih-Fong Chen

Mechanism of action of the novel anticancer agent 6-fluoro-2-(2'-fluoro-1,1'-biphenyl-4-yl)-3-methyl-4-quinolinecarbo xylic acid sodium salt (NSC 368390): inhibition of de novo pyrimidine nucleotide biosynthesis.

Shih-Fong Chen, Regina L. Ruben, Daniel L. Dexter · PubMed · 1986 · 141 citations

Pyrimidine Biosynthesis, Chemoprevention Strategy, Cell Culture +20

Effects on DNA integrity and apoptosis induction by a novel antitumor sesquiterpene drug, 6-hydroxymethylacylfulvene (HMAF, MGI 114)

Jan M. Woynarowski, Cheryl Napier, Steven K. Koester et al. · Biochemical Pharmacology · 1997 · 100 citations

Medicinal Chemistry, Apoptosis Induction, Oncogenic Agent +11

Inhibition of dihydroorotate dehydrogenase activity by brequinar sodium.

Shih-Fong Chen, Frank W. Perrella, D L Behrens et al. · PubMed · 1992 · 84 citations

Ubiquinone Q6, Medicinal Chemistry, Pharmaceutical Chemistry +15

Comparison of In Vitro Activities of Camptothecin and Nitidine Derivatives against Fungal and Cancer Cells

Maurizio Del Poeta, Shih-Fong Chen, Daniel D. Von Hoff et al. · Antimicrobial Agents and Chemotherapy · 1999 · 72 citations · Full text

Human Telomerase Inhibition by 7-Deaza-2‘-deoxypurine Nucleoside Triphosphates

Terace M. Fletcher, Miguel Salazar, Shih-Fong Chen · Biochemistry · 1996 · 63 citations