Costimulatory molecules B7-1 and B7-2 on CSF cells in multiple sclerosis and optic neuritis

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

Vijay K. Kuchroo, Mercy Prabhu Das, Julia A. Brown et al. · Cell · 1995 · 1.7K citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Long-Term Survival of Xenogeneic Pancreatic Islet Grafts Induced by CTLA4lg

Deborah J. Lenschow, Yijun Zeng, J. Richard Thistlethwaite et al. · Science · 1992 · 1.1K citations

Life Sciences, Endocrinology, Immunology +17

Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors

P S Linsley, JoAnne L. Greene, William Brady et al. · Immunity · 1994 · 972 citations

Life Sciences, Immunology, Molecular Biology +15

Immunosuppression in Vivo by a Soluble Form of the CTLA-4 T Cell Activation Molecule

Peter S. Linsley, Philip M. Wallace, Jennifer Johnson et al. · Science · 1992 · 806 citations

Life Sciences, Immunology, Autoimmunity +16

The adhesion molecule and cytokine profile of multiple sclerosis lesions

Barbara Cannella, Cedric S. Raine · Annals of Neurology · 1995 · 762 citations

Life Sciences, Immunology, Neurology +17