The Endocannabinoids Anandamide and Virodhamine Modulate the Activity of the Candidate Cannabinoid Receptor GPR55

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

William A. Devane, Aviva Breuer, Roger G. Pertwee et al. · Science · 1992 · 5.6K citations

Life Sciences, Neuroscience, Pharmacology +15

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures.

Emanuela Bonfoco, Dimitri Krainc, Maria Ankarcrona et al. · Proceedings of the National Academy of Sciences · 1995 · 2K citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

The orphan receptor GPR55 is a novel cannabinoid receptor

Erik Ryberg, Niklas Larsson, S. Sjögren et al. · British Journal of Pharmacology · 2007 · 1.6K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

Jane E. Lauckner, Jill B. Jensen, Huei-Ying Chen et al. · Proceedings of the National Academy of Sciences · 2008 · 702 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Characterization of a Novel Endocannabinoid, Virodhamine, with Antagonist Activity at the CB1 Receptor

Amy C. Porter, John‐Michael Sauer, Michael D. Knierman et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 610 citations

Medicine, Neurobiology, Pharmacology +10