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Intranasal c-di-GMP-adjuvanted plant-derived H5 influenza vaccine induces multifunctional Th1 CD4+ cells and strong mucosal and systemic antibody responses in mice

VaccinationSystemic Antibody ResponsesCross-protectionMucosal VaccinationVaccine DevelopmentImmunologyCd4 T Cell ResponsesInfluenza VaccineVaccine DesignFlu VaccinationMedicineStrong MucosalInfluenza Vaccines