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A combination of weakly stabilizing mutations with a disulfide bridge in the α-helix region of Trichoderma reesei endo-1,4-β-xylanase II increases the thermal stability through synergism

Biochemistryα-Helix RegionProtein FoldingNatural SciencesDirected EvolutionMolecular BiologyDisulfide BridgeStructure-function Enzyme KineticsMedicineThermal StabilityStructural Biology