Hydrolysis of ibuprofenoyl-CoA and other 2-APA-CoA esters by human acyl-CoA thioesterases-1 and -2 and their possible role in the chiral inversion of profens

Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase.

Jane A. Mitchell, Pravit Akarasereenont, Christoph Thiemermann et al. · Proceedings of the National Academy of Sciences · 1993 · 1.7K citations · Full text

Intact Cells, Immunology, Pharmacotherapy +17

The direct linear plot. A new graphical procedure for estimating enzyme kinetic parameters

Robert Eisenthal, Athel Cornish‐Bowden · Biochemical Journal · 1974 · 1.6K citations · Full text

Biophysical Modeling, Molecular Biology, Direct Linear Plot +19

Ellman's reagent: 5,5′-dithiobis(2-nitrobenzoic acid)—a reexamination

Peter W. Riddles, Robert L. Blakeley, Burt Zerner · Analytical Biochemistry · 1979 · 1K citations

2-Nitrobenzoic Acid, Engineering, Organic Chemistry +3

Molar absorption coefficients for the reduced Ellman reagent: reassessment

Peter Eyer, Franz Worek, Daniela Kiderlen et al. · Analytical Biochemistry · 2003 · 494 citations

State Estimation, Engineering, Physics +5

Statistical considerations in the estimation of enzyme kinetic parameters by the direct linear plot and other methods

Athel Cornish‐Bowden, Robert Eisenthal · Biochemical Journal · 1974 · 392 citations · Full text

Engineering, Direct Linear Plot, Metabolic Model +18