Concepedia

Esterase-mediated Hydrolysis

Esterase-Mediated Hydrolysis is a metabolic reaction in which ester bonds in xenobiotic compounds are cleaved by esterase enzymes, distinguishing it from other biotransformation pathways through its specificity for ester substrates and its role in the detoxification or activation of pesticides.

1.3K

Publications

50.8K

Citations

4.3K

Authors

1.1K

Institutions

Publications per year

2017–2026

104

Parents

Publications

1.3K

Serum esterases. 1. Two types of esterase (A and B) hydrolysing <i>p</i>-nitrophenyl acetate, propionate and butyrate, and a method for their determination

W. N. Aldridge · Biochemical Journal · 1953 · 742 citations · Full text

, , +11

Enzyme-Responsive Snap-Top Covered Silica Nanocontainers

Kaushik Patel, Sarah Angelos, William R. Dichtel et al. · Journal of the American Chemical Society · 2008 · 572 citations

, , +17

Serum esterases. 2. An enzyme hydrolysing diethyl <i>p</i>-nitrophenyl phosphate (E 600) and its identity with the A-esterase of mammalian sera

W. N. Aldridge · Biochemical Journal · 1953 · 447 citations · Full text

, , +12

Species Difference of Esterase Expression and Hydrolase Activity in Plasma

Fatma Goksin Bahar, Kayoko Ohura, Takuo Ogihara et al. · Journal of Pharmaceutical Sciences · 2012 · 284 citations

, , +14

Cocaine metabolism: Cocaine and norcocaine hydrolysis by liver and serum esterases

David J. Stewart, T. Inaba, Maria Lucassen et al. · Clinical Pharmacology & Therapeutics · 1979 · 283 citations

, , +13

1–5 of 1.3K

Authors

4.3K

  1. PB
    Peter Biely

    Slovak Academy of Sciences, Slovakia

    16 publications · 833 citations

    15

    h-index

  2. JG
    John G. Oakeshott

    Commonwealth Scientific and Industrial Research Organisation, Australia

    17 publications · 753 citations

    15

    h-index

  3. UT
    Uwe T. Bornscheuer

    Universität Greifswald, Germany

    17 publications · 933 citations

    14

    h-index

  4. PC
    Paul Christakopoulos

    National Technical University of Athens, Greece

    14 publications · 653 citations

    14

    h-index

  5. BD
    Bruce D. Hammock

    University of California, Davis, United States

    12 publications · 553 citations

    11

    h-index

1–5 of 4.3K

Institutions

1.1K

  1. Commonwealth Scientific and Industrial Research Organisation

    Canberra, Australia

    16 h-index

    89 publications

    3.9K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    16 h-index

    48 publications

    1.7K citations

  3. University of California, Davis

    Davis, United States

    15 h-index

    59 publications

    3K citations

  4. Slovak Academy of Sciences

    Bratislava, Slovakia

    15 h-index

    30 publications

    1.3K citations

  5. National Technical University of Athens

    Athens, Greece

    13 h-index

    47 publications

    2.3K citations

  6. Chinese Academy of Sciences

    Beijing, China

    12 h-index

    48 publications

    993 citations

  7. University of Michigan

    Ann Arbor, United States

    12 h-index

    27 publications

    986 citations

  8. Universität Greifswald

    Greifswald, Germany

    12 h-index

    47 publications

    2.1K citations

1–8 of 1.1K

Venues

  1. Journal of the American Chemical Society

    JACS · 41 publications · 2.9K citations

    26

    h-index

  2. Applied Microbiology and Biotechnology

    34 publications · 1.5K citations

    23

    h-index

  3. Pesticide Biochemistry and Physiology

    PBP · 27 publications · 1.1K citations

    22

    h-index

  4. Biochemical Pharmacology

    25 publications · 929 citations

    19

    h-index

  5. Journal of Molecular Catalysis B Enzymatic

    30 publications · 932 citations

    18

    h-index

1–5