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Increased Glomerular and Tubular Expression of Transforming Growth Factor-β1, Its Type II Receptor, and Activation of the Smad Signaling Pathway in the db/db Mouse

Soon Won Hong, Motohide Isono, Sheldon Chen, M. Carmen Iglesias‐de la Cruz, Dong Cheol Han, Fuad N. Ziyadeh

American Journal Of Pathology · 2001 · 195 citations · 36 references

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36

Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db/db Mice

Hong Chen, Olga Charlat, Louis A. Tartaglia et al. · Cell · 1996 · 2.2K citations · Full text

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Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene

Sylviane Dennler · The EMBO Journal · 1998 · 1.8K citations · Full text

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Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

Herbert Y. Lin, Xiao‐Fan Wang, Elinor Ng-Eaton et al. · Cell · 1992 · 1.1K citations

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Human Smad3 and Smad4 Are Sequence-Specific Transcription Activators

Leigh Zawel, Jia Le Dai, Phillip Buckhaults et al. · Molecular Cell · 1998 · 934 citations · Full text

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Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-β antibody in <i>db/db</i> diabetic mice

Fuad N. Ziyadeh, Brenda B. Hoffman, Dong Cheol Han et al. · Proceedings of the National Academy of Sciences · 2000 · 911 citations · Full text

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