Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-β antibody in<i>db/db</i>diabetic mice

Fuad N. Ziyadeh, Brenda B. Hoffman, Dong Cheol Han, +6

Proceedings of the National Academy of Sciences

ACE and ACE2 Activity in Diabetic Mice

Jan Wysocki, Minghao Ye, María José Soler, +6

Diabetes

Nephrotoxicity of immune checkpoint inhibitors beyond tubulointerstitial nephritis: single-center experience

Omar Mamlouk, Umut Selamet, Shana Machado, +16

Journal for ImmunoTherapy of Cancer

Effects of high glucose and TGF-β1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes

M. Carmen Iglesias‐de la Cruz, Fuad N. Ziyadeh, Motohide Isono, +5

Kidney International

AngiogenesisHigh GlucoseMouse PodocytesCollagen IvPhysiology +9

Hydrogen peroxide increases extracellular matrix mRNA through TGF-β in human mesangial cells

M. Carmen Iglesias‐de la Cruz, María Piedad Ruiz‐Torres, José Alcamı́, +6

Kidney International

Tissue DevelopmentPhysiologyExtracellular MatrixHuman Mesangial CellsExtracellular Matrix Mrna +9

Blockade of Vascular Endothelial Growth Factor Signaling Ameliorates Diabetic Albuminuria in Mice

Sun Hee Sung, Fuad N. Ziyadeh, Amy Wang, +3

Journal of the American Society of Nephrology

InflammationRenal FunctionMicrovascular DysfunctionChronic Kidney DiseaseAtherosclerosis +16

Retooling the Creatinine Clearance Equation to Estimate Kinetic GFR when the Plasma Creatinine Is Changing Acutely

Sheldon Chen

Journal of the American Society of Nephrology

UrologyRenal FunctionKidney ResearchMedicineCreatinine Clearance Equation +12

Increased Glomerular and Tubular Expression of Transforming Growth Factor-β1, Its Type II Receptor, and Activation of the Smad Signaling Pathway in the db/db Mouse

Soon Won Hong, Motohide Isono, Sheldon Chen, +3

American Journal Of Pathology

GlomerulonephritisDb/db MouseMolecular PhysiologySignal TransductionDevelopmental Biology +11

Smad pathway is activated in the diabetic mouse kidney and Smad3 mediates TGF-β-induced fibronectin in mesangial cells

Motohide Isono, Sheldon Chen, Soon Won Hong, +2

Biochemical and Biophysical Research Communications

FibrosisSignal TransductionMolecular PhysiologySmad PathwayMedicine +11

Leptin stimulates type I collagen production in db/db mesangial cells: Glucose uptake and TGF-β type II receptor expression

Dong Cheol Han, Motohide Isono, Sheldon Chen, +4

Kidney International

Developmental BiologyMolecular PhysiologyDb/db Mesangial CellsGrowth HormoneGlucose Uptake +10