Can autophagy promote longevity?

Autophagy in the Pathogenesis of Disease

Beth Levine, Guido Kroemer · Cell · 2008 · 7K citations · Full text

Life Sciences, Cell Biology, Pathobiology +10

Resveratrol improves health and survival of mice on a high-calorie diet

Joseph A. Baur, Kevin Pearson, Nathan L. Price et al. · Nature · 2006 · 4.2K citations · Full text

Life Sciences, Nutrition, Nutritional Sciences +11

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

Taichi Hara, Kenji Nakamura, Makoto Matsui et al. · Nature · 2006 · 3.8K citations

Life Sciences, Neurobiology, Neuroscience +12

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Konrad T. Howitz, Kevin J. Bitterman, Haim Cohen et al. · Nature · 2003 · 3.8K citations

Education, Genetics, Molecular Biology +12

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Randy Strong, Z. Dave Sharp, James F. Nelson et al. · Nature · 2009 · 3.7K citations · Full text

Education, Genetics, Nutrition +15