Hypermethylation of CpG islands is more prevalent than hypomethylation across the entire genome in breast carcinogenesis

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

Rafael A. Irizarry, Christine Ladd‐Acosta, Bo Wen et al. · Nature Genetics · 2009 · 2.2K citations · Full text

Chromatin, Similar Hypo-, Medicine +11

Role for DNA methylation in genomic imprinting

Rudolf Jaenisch · Nature · 1993 · 1.9K citations

Chromatin, Epigenetic Change, Genetics +5

Role for DNA methylation in genomic imprinting

E. Li, Caroline Beard, Rudolf Jaenisch · Trends in Genetics · 1994 · 1.7K citations

Chromatin, Epigenetic Change, Genetics +5

Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification.

Minoru Toyota, Coty Ho, Nita Ahuja et al. · PubMed · 1999 · 470 citations

Engineering, Epigenetic Change, Genetics +19

Methylation profiling of CpG islands in human breast cancer cells

Tim H-M. Huang · Human Molecular Genetics · 1999 · 427 citations

Cpg Island Hypermethylation, Breast Oncology, Epigenetic Change +18