DNA demethylation is necessary for the epigenetic reprogramming of somatic cell nuclei

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

Hitoshi Niwa, Jun‐ichi Miyazaki, Austin Smith · Nature Genetics · 2000 · 3.6K citations

Life Sciences, Cell Biology, Developmental Biology +13

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

Bruno Luckow, Günther Schütz · Nucleic Acids Research · 1987 · 1.8K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

The Developmental Capacity of Nuclei taken from Intestinal Epithelium Cells of Feeding Tadpoles

J. B. Gurdon · Development · 1962 · 1.1K citations

Life Sciences, Biology, Developmental Biology +13

Somatic cell nuclear transfer

I. Wilmut, Nathalie Beaujean, Paul A. De Sousa et al. · Nature · 2002 · 541 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +7

Oct4 distribution and level in mouse clones: consequences for pluripotency

Michele Boiani, Sigrid Eckardt, Hans R. Schöler et al. · Genes & Development · 2002 · 517 citations · Full text

Life Sciences, Developmental Biology, Genetics +17