Concepedia

Activation of interleukin-6/signal transducer and activator of transcription 3 by human papillomavirus early proteins 6 induces fibroblast senescence to promote cervical tumourigenesis through autocrine and paracrine pathways in tumour microenvironment

Chun‐Xia Ren, Xi Cheng, Bei Lü, Gong Yang

European Journal of Cancer · 2013 · 85 citations · 39 references

DOI

Concepts

References

39

Human papillomavirus is a necessary cause of invasive cervical cancer worldwide

Jan M.M. Walboomers, Marcel V. Jacobs, M. Michele Manos et al. · The Journal of Pathology · 1999 · 9K citations · Full text

, , +16

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

Françis Rodier, Jean‐Philippe Coppé, Christopher K. Patil et al. · Nature Cell Biology · 2009 · 2.2K citations · Full text

, , +14

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

Sergei I. Grivennikov, Eliad Karin, Janoš Terzić et al. · Cancer Cell · 2009 · 2.1K citations · Full text

, , +16

Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network

Thomas Kuilman, Chrysiis Michaloglou, Liesbeth C.W. Vredeveld et al. · Cell · 2008 · 2K citations · Full text

, , +14

Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging

Ana Krtolica, Simona Parrinello, Stephen Lockett et al. · Proceedings of the National Academy of Sciences · 2001 · 1.7K citations · Full text

, , +17