Perioperative immune responses in cancer patients undergoing digestive surgeries

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

Timothy R. Mosmann, Holly Cherwinski, M W Bond et al. · The Journal of Immunology · 1986 · 7.5K citations

Adaptive Immune System, T-regulatory Cell, Cellular Immunology +19

Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations.

Peter Openshaw, Ellen Murphy, Nancy Hosken et al. · The Journal of Experimental Medicine · 1995 · 545 citations · Full text

Major Injury Leads to Predominance of the T Helper-2 Lymphocyte Phenotype and Diminished Interleukin-12 Production Associated with Decreased Resistance to Infection

S.T. O’Sullivan, James A. Lederer, Alan Horgan et al. · Annals of Surgery · 1995 · 497 citations · Full text

Surgical stress induces a shift in the type-1/type-2 T-helper cell balance, suggesting down-regulation of cell-mediated and up-regulation of antibody-mediated immunity commensurate to the trauma

Dorothee Decker, Martin Schöndorf, F. Bidlingmaier et al. · Surgery · 1996 · 386 citations

Inflammation, Surgical Stress, Autoimmune Disease +12

Distinct mechanisms of immunosuppression as a consequence of major surgery

T. Hensler, H. Hecker, Klaus Heeg et al. · Infection and Immunity · 1997 · 335 citations · Full text

Clinical Immunology, Distinct Mechanisms, T-regulatory Cell +23