Endotoxin tolerance: In vivo regulation of tumor necrosis factor and interleukin-1 synthesis is at the transcriptional level

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

John David Dignam, Russell M. Lebovitz, R G Roeder · Nucleic Acids Research · 1983 · 11.6K citations · Full text

Engineering, Rna Polymerase Ii, Isolated Mammalian Nuclei +19

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

Michael E. Greenberg, Edward B. Ziff · Nature · 1984 · 3.2K citations

Transcriptional Regulation, Developmental Biology, Signal Transduction +12

Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages.

Alexander N. Shakhov, Martine A. Collart, P Vassalli et al. · The Journal of Experimental Medicine · 1990 · 820 citations · Full text

Primary Macrophages, Immunology, Immune Regulation +21

Mouse actin messenger RNAs. Construction and characterization of a recombinant plasmid molecule containing a complementary DNA transcript of mouse alpha-actin mRNA.

A Minty, M. Caravatti, B. Robert et al. · Journal of Biological Chemistry · 1981 · 433 citations · Full text

Muscle Function, Molecular Biology, Cytoskeleton +18

Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor.

Y. Nophar, O. Kemper, Cord Brakebusch et al. · The EMBO Journal · 1990 · 332 citations · Full text

Inflammation, Soluble Form, Immunology +8