Concepedia

Relationship of systemic exposure to unbound docetaxel and neutropenia

Sharyn D. Baker, Jie Li, A TENTIJE, William D. Figg, Wilfried J. Graveland, Jaap Verweij, Alex Sparreboom

Clinical Pharmacology & Therapeutics · 2005 · 90 citations · 18 references

DOI

Abstract

Exposure to unbound docetaxel is closely related to drug-induced hematologic toxicity and should be considered in future pharmacologic investigations.

References

18

A wilcoxon‐type test for trend

Jack Cuzick · Statistics in Medicine · 1985 · 1.9K citations

Model of Chemotherapy-Induced Myelosuppression With Parameter Consistency Across Drugs

Lena E. Friberg, Anja Henningsson, Hugo Maas et al. · Journal of Clinical Oncology · 2002 · 523 citations

Population pharmacokinetics/pharmacodynamics of docetaxel in phase II studies in patients with cancer.

René Bruno, Darcy A. Hille, A. Riva et al. · Journal of Clinical Oncology · 1998 · 418 citations

A population pharmacokinetic model for docetaxel (Taxotere®): Model building and validation

René Bruno, Nicole Vivier, J. Vergniol et al. · Journal of Pharmacokinetics and Biopharmaceutics · 1996 · 264 citations

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A comparison of commonly used polyethoxylated pharmaceutical excipients on their ability to inhibit P‐glycoprotein activity in vitro

Erin Hugger, Barbara Novak, Philip S. Burton et al. · Journal of Pharmaceutical Sciences · 2002 · 235 citations

, , +8