Stress-induced senescence in human and rodent astrocytes

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

Education, Cell Biology, Molecular Biology +15

Telomeres shorten during ageing of human fibroblasts

Calvin B. Harley, A. B. Futcher, Carol W. Greider · Nature · 1990 · 5.7K citations

Education, Cell Biology, Genetics +11

Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence

Masashi Narita, Sabrina Nuñez, Édith Heard et al. · Cell · 2003 · 2.2K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Cloning of Senescent Cell-Derived Inhibitors of DNA Synthesis Using an Expression Screen

Asao Noda, Yi Ning, Susan Venable et al. · Experimental Cell Research · 1994 · 1.4K citations

Life Sciences, Biotechnology, Molecular Biology +7

Regulation of p16<i>^CDKN2</i> Expression and Its Implications for Cell Immortalization and Senescence

Eiji Hara, Rosalind Smith, David Parry et al. · Molecular and Cellular Biology · 1996 · 724 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17