Valproic acid improved in vitro development of pig cloning embryos but did not improve survival of cloned pigs to adulthood

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

Danwei Huangfu, René Maehr, Wenjun Guo et al. · Nature Biotechnology · 2008 · 1.6K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

Production of α-1,3-Galactosyltransferase Knockout Pigs by Nuclear Transfer Cloning

Liangxue Lai, Donna Kolber‐Simonds, Kwang‐Wook Park et al. · Science · 2002 · 1.3K citations

Veterinary Medicine, Biotechnology, Genetics +17

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

Danwei Huangfu, Kenji Osafune, René Maehr et al. · Nature Biotechnology · 2008 · 1.3K citations

Life Sciences, Cell Biology, Developmental Biology +15

Disruption of the <i>CFTR</i> Gene Produces a Model of Cystic Fibrosis in Newborn Pigs

Christopher S. Rogers, David A. Stoltz, David K. Meyerholz et al. · Science · 2008 · 748 citations

Medicine, Genetics, Molecular Genetics +17

Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs

Yifan Dai, Todd Vaught, Jeremy Boone et al. · Nature Biotechnology · 2002 · 710 citations

Agriculture, Genetics, Molecular Genetics +9