Concepedia

Distinct Properties of Telmisartan on Agonistic Activities for Peroxisome Proliferator-Activated Receptor γ among Clinically Used Angiotensin II Receptor Blockers: Drug-Target Interaction Analyses

Hirotoshi Kakuta, Eiji Kurosaki, Tatsuya Niimi, Katsuhiko Gato, Yuko Kawasaki, Akira Suwa, Kazuya Honbou, Tomohiko Yamaguchi, Hiroyuki Okumura, Masanao Sanagi,

Journal of Pharmacology and Experimental Therapeutics · 2014 · 26 citations · 48 references

DOI

Concepts

References

48

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

Toshimasa Yamauchi, Junji Kamon, Hironori Waki et al. · Nature Medicine · 2001 · 4.9K citations

, , +14

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

Toshimasa Yamauchi, Junji Kamon, Yasuhiko Minokoshi et al. · Nature Medicine · 2002 · 4.2K citations

, , +16

Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

Peter Tontonoz, Erding Hu, Bruce M. Spiegelman · Cell · 1994 · 3.5K citations

, , +12

PPARγ Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein

Norikazu Maeda, Masahiko Takahashi, Tohru Funahashi et al. · Diabetes · 2001 · 1.7K citations · Full text

, , +14

Identification of Telmisartan as a Unique Angiotensin II Receptor Antagonist With Selective PPARγ–Modulating Activity

Stephen C. Benson, Harrihar A. Pershadsingh, Christopher Ho et al. · Hypertension · 2004 · 1.1K citations

, , +17