High-performance liquid chromatographic analysis of mevinolin as mevinolinic acid in fermentation broths

Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.

Alfred W. Alberts, J Chen, G. W. Kuron et al. · Proceedings of the National Academy of Sciences · 1980 · 1.6K citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase

Michael S. Brown, J R Faust, Joseph L. Goldstein et al. · Journal of Biological Chemistry · 1978 · 557 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

Determination of mevinolin and mevinolinic acid in plasma and bile by reversed-phase high-performance liquid chromatography

R.J. Stubbs, Michael S. Schwartz, W.F. Bayne · Journal of Chromatography B Biomedical Sciences and Applications · 1986 · 63 citations

Pharmacy, Chemistry, Pharmacology +12

Mutants of a lovastatin-hyperproducingAspergillus terreus deficient in the production of sulochrin

Victor A. Vinci, T. D. Hoerner, Allen D. Coffman et al. · Journal of Industrial Microbiology & Biotechnology · 1991 · 61 citations

Life Sciences, Biology, Microbiology +4

Determination of Lovastatin (mevinolin) and mevinolinic acid in fermentation liquids

Roman Kysilka, Vladimír Křen · Journal of Chromatography A · 1993 · 33 citations

Agriculture, Food Science, Microbiology +9