Binding and Degradation of Low Density Lipoproteins by Cultured Human Fibroblasts

Joseph L. Goldstein, Michael S. Brown · Journal of Biological Chemistry · 1974

Lipid AnalysisHyperlipidemiaLow Density+19

Receptor-Mediated Control of Cholesterol Metabolism

Michael S. Brown, Joseph L. Goldstein · Science · 1976

Cholesterol MetabolismSignal TransductionOxysterol+5

ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogensis produced by Penicillium citrinum.

Akira Endo, Masao Kuroda, Yoshio Tsujita · The Journal of Antibiotics · 1976

Competitive inhibition of 3‐hydroxy‐3‐methylglutaryl coenzyme a reductase by ML‐236A and ML‐236B fungal metabolites, having hypocholesterolemic activity

Akira Endo, Masao Kuroda, Kazuhiko Tanzawa · FEBS Letters · 1976

Industrial MycologyAldo-keto ReductaseBiochemistry+7

Familial hypercholesterolemia: Defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase activity

Michael S. Brown, Joseph L. Goldstein · Proceedings of the National Academy of Sciences · 1974

GeneticsHyperlipidemiaNormal Human Subjects+17