Isamu Kaneko

Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase

Michael S. Brown, J R Faust, Joseph L. Goldstein et al. · Journal of Biological Chemistry · 1978 · 557 citations · Full text

Aldo-keto Reductase, 3-Hydroxy-3-methylglutaryl Coenzyme, Biochemistry +8

Drastic neuronal loss in vivo by β-amyloid racemized at Ser26 residue: conversion of non-toxic [D-Ser26]β-amyloid 1–40 to toxic and proteinase-resistant fragments

Isamu Kaneko, K Morimoto, Tomoko Kubo · Neuroscience · 2001 · 93 citations

Neurodegenerative Diseases, Molecular Neuroscience, Ser26 Residue +11

Co-injection of β-amyloid with ibotenic acid induces synergistic loss of rat hippocampal neurons

K Morimoto, Kouji Yoshimi, T Tonohiro et al. · Neuroscience · 1998 · 76 citations

Neurodegenerative Diseases, Medicine, Neuropharmacology +7

Inhibition of the alternative pathway of human complement <i>in vitro</i> by a natural microbial product, complestatin.

Isamu Kaneko, D T Fearon, K. Frank Austen · The Journal of Immunology · 1980 · 67 citations · Full text

A practical scale evaluation of catalysts for the selective reduction of NO with organic substances using a diesel exhaust

Akira Obuchi, Isamu Kaneko, Junko Oi et al. · Applied Catalysis B: Environmental · 1998 · 48 citations