Concepedia

High-Affinity Small Molecule Inhibitors of T Cell Costimulation: Compounds for Immunotherapy

Philip Huxley, Deborah H. Sutton, Phillip Debnam, Ian R. Matthews, Joanna E. Brewer, Jennifer Rose, Matthew Trickett, Daniel Williams, Torben B. Andersen, Brendan J. Classon

Chemistry & Biology · 2004 · 37 citations · 48 references

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48

Enhancement of Antitumor Immunity by CTLA-4 Blockade

Dana R. Leach, Matthew F. Krummel, James P. Allison · Science · 1996 · 3.9K citations

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Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity

John O’Brien, Ian D. Wilson, Terry C. Orton et al. · European Journal of Biochemistry · 2000 · 3.4K citations · Full text

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B7/CD28 Costimulation Is Essential for the Homeostasis of the CD4+CD25+ Immunoregulatory T Cells that Control Autoimmune Diabetes

Deborah J. Lenschow, Lesley Rhee, Neda Ashourian et al. · Immunity · 2000 · 2K citations · Full text

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B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

Vijay K. Kuchroo, Mercy Prabhu Das, Julia A. Brown et al. · Cell · 1995 · 1.7K citations · Full text

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CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

Fiona Harding, James G. McArthur, Jane A. Gross et al. · Nature · 1992 · 1.6K citations

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