Concepedia

Philip Huxley

PH

Statistics

Publications

12

Citations

750

H-Index

12

Active since

1990

Affiliations

Bicycle Therapeutics (United Kingdom)(Current)

Novartis (Switzerland)

Max Planck Institute of Biochemistry

Philip Huxley is an author at Bicycle Therapeutics (United Kingdom) specializing in drug discovery, pharmacology, and medicinal chemistry.

Publications per year

1990–2024

12

Publications

12

Structure determination and analysis of human neutrophil collagenase complexed with a hydroxamate inhibitor

Frank Grams, Mike Crimmin, Laurie Hinnes et al. · Biochemistry · 1995 · 166 citations

, , +11

The application of molecular similarity calculations

Catherine Burt, W. Graham Richards, Philip Huxley · Journal of Computational Chemistry · 1990 · 125 citations

, , +10

MMAE Delivery Using the <i>Bicycle</i> Toxin Conjugate BT5528

Gavin Bennett, Amy Brown, Gemma Mudd et al. · Molecular Cancer Therapeutics · 2020 · 98 citations

, , +13

1.8‐Å Crystal Structure of the Catalytic Domain of Human Neutrophil Collagenase (Matrix Metalloproteinase‐8) Complexed with a Peptidomimetic Hydroxamate Primed‐Side Inhibitor with a Distinct Selectivity Profile

Michael Betz, Philip Huxley, Stephen J. Davies et al. · European Journal of Biochemistry · 1997 · 79 citations · Full text

, , +16

Identification and Optimization of EphA2-Selective Bicycles for the Delivery of Cytotoxic Payloads

Gemma Mudd, Amy Brown, Liuhong Chen et al. · Journal of Medicinal Chemistry · 2020 · 79 citations · Full text

, , +14

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