Concepedia

CoMFA and CoMSIA investigations of dopamine D3 receptor ligands leading to the prediction, synthesis, and evaluation of rigidized FAUC 365 analogues

Ismail Salama, Karin Schlotter, Wolfgang Utz, Harald Hübner, Peter Gmeiner, Frank M. Boeckler

Bioorganic & Medicinal Chemistry · 2006 · 20 citations · 33 references

DOI

Concepts

References

33

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

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Iterative partial equalization of orbital electronegativity—a rapid access to atomic charges

Johann Gasteiger, Mario Marsili · Tetrahedron · 1980 · 4.1K citations

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Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins

Richard D. Cramer, David E. Patterson, Jeffrey D. Bunce · Journal of the American Chemical Society · 1988 · 3.9K citations

, , +14

Validation of the general purpose tripos 5.2 force field

Matthew Clark, Richard D. Cramer, N. Van Opdenbosch · Journal of Computational Chemistry · 1989 · 2.8K citations

, , +17

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

Pierre Sokoloff, Bruno Giros, Marie‐Pascale Martres et al. · Nature · 1990 · 2.6K citations · Full text

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