Harald Hübner

Structure-based discovery of opioid analgesics with reduced side effects

Aashish Manglik, Henry J. Lin, Dipendra K. Aryal et al. · Nature · 2016 · 925 citations · Full text

Health Sciences, Pain Medicine, Structure-based Discovery +8

Activation and allosteric modulation of a muscarinic acetylcholine receptor

Andrew C. Kruse, Aaron M. Ring, Aashish Manglik et al. · Nature · 2013 · 896 citations · Full text

Functional Selectivity, Medicine, Synaptic Transmission +6

Interactive SAR Studies:  Rational Discovery of Super-Potent and Highly Selective Dopamine D3 Receptor Antagonists and Partial Agonists

Laura Bettinetti, Karin Schlotter, Harald Hübner et al. · Journal of Medicinal Chemistry · 2002 · 193 citations · Full text

Combinatorial Chemistry, Drug Target, Phenyl Substituents +17

Conjugated Enynes as Nonaromatic Catechol Bioisosteres:  Synthesis, Binding Experiments, and Computational Studies of Novel Dopamine Receptor Agonists Recognizing Preferentially the D₃Subtype

Harald Hübner, Christian Haubmann, Wolfgang Utz et al. · Journal of Medicinal Chemistry · 2000 · 167 citations · Full text

Structure-based discovery of nonopioid analgesics acting through the α _2A -adrenergic receptor

Elissa A. Fink, Jun Xu, Harald Hübner et al. · Science · 2022 · 142 citations · Full text