Circadian Regulator CLOCK Is a Histone Acetyltransferase

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

Shin‐ichiro Imai, Christopher M. Armstrong, Matt Kaeberlein et al. · Nature · 2000 · 3.5K citations

Histone Modifications, Chromatin, Transcriptional Regulation +12

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

Vasily Ogryzko, R. Louis Schiltz, Valya Russanova et al. · Cell · 1996 · 2.9K citations · Full text

Chromatin, Transcriptional Regulation, Chromatin Structure +10

Obesity and Metabolic Syndrome in Circadian <i>Clock</i> Mutant Mice

Fred W. Turek, Corinne E. Joshu, Akira Kohsaka et al. · Science · 2005 · 2.4K citations · Full text

Homeostatic Mechanism, Pacemaker Neurons, Clock Transcription Factor +20

Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock

Satchidananda Panda, Marina P. Antoch, Brooke H. Miller et al. · Cell · 2002 · 2.3K citations · Full text

Transcriptional Regulation, Alertness, Developmental Biology +10

A Serum Shock Induces Circadian Gene Expression in Mammalian Tissue Culture Cells

Aurélio Balsalobre, Francesca Damiola, Ueli Schibler · Cell · 1998 · 2K citations · Full text

Developmental Biology, Cell Regulation, Medicine +7